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多種修護肌膚的礦物質微量元素(銅、錳、鋅、矽、鈣、鎂、鉀、鈉/海泉水)

Simplism簡單保養2021-09-28保養專欄,抗痘成份
多種修護肌膚的礦物質微量元素

海水中蘊含多種的礦物質，礦物質對皮膚的健康具有有益特性，而保養品也常常添加礦物質當作功效成分。 來自法國布列塔尼的海泉水經過特殊處理之後，減少鹽分的含量，留下對皮膚有益的礦物質成分 如：銅、錳、鋅、矽、鈣、鎂、鉀、鈉等。

 

以下是礦物質應用於皮膚之文獻：

海水中的礦物質

鈣(Ca)+鎂(Mg)+鈉(Na)+鉀(K)+鐵(Fe)

來自深海基岩的礦泉水(10%)(富含鈣、鎂、鈉、鉀、鐵等礦物質)有助減緩異位性皮膚炎的症狀如：水腫、紅斑、乾燥、瘙癢和經皮水分散失的嚴重程度； 另篇研究指出，10%高濃度礦泉水有助於促進傷口癒合及改善異位性皮膚炎症狀。 將海水/礦泉水應用於保養品當中，研究指出，含2.5%死海水的皮膚乳液對於兒童異位性皮膚炎的皮膚屏障功能和水合作用有益。 而海水中的個別礦物質應用於皮膚，也有許多文獻支持，包括：異位性皮膚炎的發炎情形、促進皮膚傷口癒合及皮膚屏障功能的改善皆有有益的幫助。

 

錳(Mn)+碘(I)

含有錳和碘離子的酸性溶液(pH 2.0-3.0)在臨床上可用於治療由金黃色葡萄球菌引起的皮膚病。

 

鋅(Zn)

鋅是一種必需礦物質，在皮膚病學領域已被廣泛研究，用於治療多種皮膚病。最近的研究指出，鋅可能是手術後傷口癒合的有益治療選擇。

 

鈣(Ca)

鈣除了作為止血過程中的關鍵凝血因子外，鈣離子還被證明是在傷口癒合過程中指導不同類型細胞功能的關鍵因子，能夠調節皮膚傷口癒合。

 

鎂(Mg)

抑制蘭格罕細胞的抗原呈現能力，因此可能有助於治療炎症性皮膚病；在高鎂含量的死海鹽溶液(5%)中沐浴可改善皮膚屏障功能、增強皮膚水分，並減少乾性異位性皮膚炎的粗糙、發紅情形。
研究指出，外用含2%鎂的乳膏對於嬰幼兒尿布皮膚炎及尿布疹具有改善作用。

 

鎂(Mg)+矽(Si)

研究指出，鎂離子及矽離子能刺激皮膚組織的再生，有助於皮膚傷口癒合。

 

鈣(Ca)+鎂(Mg)

氯化鎂和氯化鈣的水溶液能有效地加速皮膚屏障恢復。

 

鈣(Ca)+鎂(Mg)+錳(Mn)

研究指出，含有鈣、鎂、錳等礦物質的水溶液能夠幫助保護被紫外線(UVB)損傷的皮膚屏障功能。

 

銅(Cu)

文獻指出，銅離子具抗氧化及維持皮膚屏障的功效。

引用文獻：

  1. Eau de Source Marine原廠資料
  2. Guillerme J-B, Couteau C, Coiffard L. Applications for Marine Resources in Cosmetics. Cosmetics. 2017; 4(3):35.
  3. Bak JP, Kim YM, Son J, Kim CJ, Kim EH. Application of concentrated deep sea water inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice. BMC Complement Altern Med. 2012;12:108. Published 2012 Jul 26.
  4. Bajgai, Johny & Lee, Kyu. (2017). High Mineral Spring Water Promotes Skin Injury Healing in Hairless Mice. 6. 1-6.
  5. Bajgai, J., Fadriquela, A., Ara, J. et al. Balneotherapeutic effects of high mineral spring water on the atopic dermatitis-like inflammation in hairless mice via immunomodulation and redox balance. BMC Complement Altern Med 17, 481 (2017).
  6. M. Portugal-Cohen, M. Oron, E. Merrik, Z. Ma’or, D. Ben-Amitai, H. Yogev and A. Zvulunov, "A Dead Sea Water-Enriched Body Cream Improves Skin Severity Scores in Children with Atopic Dermatitis," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 1 No. 3, 2011, pp. 71-78.
  7. Polefka TG, Bianchini RJ, Shapiro S. Interaction of mineral salts with the skin: a literature survey. Int J Cosmet Sci. 2012;34(5):416-423.
  8. Inoue T, Inoue S, Kubota K. Bactericidal activity of manganese and iodide ions against Staphylococcus aureus: a possible treatment for acute atopic dermatitis. Acta Derm Venereol. 1999;79(5):360-362.
  9. Levin, N., Gray, T., Farsi, M., Dorton, D., & Miller, R. (2020). Topical Zinc May Augment Post-Operative Wound Healing, Including Following Mohs Micrographic Surgery: A Review of the Literature. SKIN The Journal of Cutaneous Medicine, 4(5), 395–403.
  10. Subramaniam T, Fauzi MB, Lokanathan Y, Law JX. The Role of Calcium in Wound Healing. International Journal of Molecular Sciences. 2021; 22(12):6486.
  11. Schempp CM, Dittmar HC, Hummler D, et al. Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines. J Invest Dermatol. 2000;115(4):680-686.
  12. Proksch E, Nissen HP, Bremgartner M, Urquhart C. Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol. 2005;44(2):151-157.
  13. Nourbakhsh SM, Rouhi-Boroujeni H, Kheiri M, et al. Effect of Topical Application of the Cream Containing Magnesium 2% on Treatment of Diaper Dermatitis and Diaper Rash in Children A Clinical Trial Study. J Clin Diagn Res. 2016;10(1):WC04-WC6.
  14. Sasaki Y, Sathi GA, Yamamoto O. Wound healing effect of bioactive ion released from Mg-smectite. Mater Sci Eng C Mater Biol Appl. 2017;77:52-57.
  15. Denda M, Katagiri C, Hirao T, Maruyama N, Takahashi M. Some magnesium salts and a mixture of magnesium and calcium salts accelerate skin barrier recovery. Arch Dermatol Res. 1999;291(10):560-563.
  16. Lee, Sung Hoon & Min, Dae & Na, Yongjoo & Shim, Jongwon & Kwon, Lee & Cho, Jun-Cheol & Lee, Hae. (2013). The Protective Effect of Mineral Water Against UVB Irradiation. Journal of the Society of Cosmetic Scientists of Korea. 39. 10.15230/SCSK.2013.39.1.039.
  17. Tamura, Bhertha. (2012). A historical review of mineral water Revisão histórica das águas termais. Surgical and Cosmetic Dermatology. 4. 254.
多種修護肌膚的礦物質微量元素

海水中蘊含多種的礦物質，礦物質對皮膚的健康具有有益特性，而保養品也常常添加礦物質當作功效成分。 來自法國布列塔尼的海泉水經過特殊處理之後，減少鹽分的含量，留下對皮膚有益的礦物質成分 如：銅、錳、鋅、矽、鈣、鎂、鉀、鈉等。

 

以下是礦物質應用於皮膚之文獻：

海水中的礦物質

鈣(Ca)+鎂(Mg)+鈉(Na)+鉀(K)+鐵(Fe)

來自深海基岩的礦泉水(10%)(富含鈣、鎂、鈉、鉀、鐵等礦物質)有助減緩異位性皮膚炎的症狀如：水腫、紅斑、乾燥、瘙癢和經皮水分散失的嚴重程度； 另篇研究指出，10%高濃度礦泉水有助於促進傷口癒合及改善異位性皮膚炎症狀。 將海水/礦泉水應用於保養品當中，研究指出，含2.5%死海水的皮膚乳液對於兒童異位性皮膚炎的皮膚屏障功能和水合作用有益。 而海水中的個別礦物質應用於皮膚，也有許多文獻支持，包括：異位性皮膚炎的發炎情形、促進皮膚傷口癒合及皮膚屏障功能的改善皆有有益的幫助。

 

錳(Mn)+碘(I)

含有錳和碘離子的酸性溶液(pH 2.0-3.0)在臨床上可用於治療由金黃色葡萄球菌引起的皮膚病。

 

鋅(Zn)

鋅是一種必需礦物質，在皮膚病學領域已被廣泛研究，用於治療多種皮膚病。最近的研究指出，鋅可能是手術後傷口癒合的有益治療選擇。

 

鈣(Ca)

鈣除了作為止血過程中的關鍵凝血因子外，鈣離子還被證明是在傷口癒合過程中指導不同類型細胞功能的關鍵因子，能夠調節皮膚傷口癒合。

 

鎂(Mg)

抑制蘭格罕細胞的抗原呈現能力，因此可能有助於治療炎症性皮膚病；在高鎂含量的死海鹽溶液(5%)中沐浴可改善皮膚屏障功能、增強皮膚水分，並減少乾性異位性皮膚炎的粗糙、發紅情形。
研究指出，外用含2%鎂的乳膏對於嬰幼兒尿布皮膚炎及尿布疹具有改善作用。

 

鎂(Mg)+矽(Si)

研究指出，鎂離子及矽離子能刺激皮膚組織的再生，有助於皮膚傷口癒合。

 

鈣(Ca)+鎂(Mg)

氯化鎂和氯化鈣的水溶液能有效地加速皮膚屏障恢復。

 

鈣(Ca)+鎂(Mg)+錳(Mn)

研究指出，含有鈣、鎂、錳等礦物質的水溶液能夠幫助保護被紫外線(UVB)損傷的皮膚屏障功能。

 

銅(Cu)

文獻指出，銅離子具抗氧化及維持皮膚屏障的功效。

引用文獻：

  1. Eau de Source Marine原廠資料
  2. Guillerme J-B, Couteau C, Coiffard L. Applications for Marine Resources in Cosmetics. Cosmetics. 2017; 4(3):35.
  3. Bak JP, Kim YM, Son J, Kim CJ, Kim EH. Application of concentrated deep sea water inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice. BMC Complement Altern Med. 2012;12:108. Published 2012 Jul 26.
  4. Bajgai, Johny & Lee, Kyu. (2017). High Mineral Spring Water Promotes Skin Injury Healing in Hairless Mice. 6. 1-6.
  5. Bajgai, J., Fadriquela, A., Ara, J. et al. Balneotherapeutic effects of high mineral spring water on the atopic dermatitis-like inflammation in hairless mice via immunomodulation and redox balance. BMC Complement Altern Med 17, 481 (2017).
  6. M. Portugal-Cohen, M. Oron, E. Merrik, Z. Ma’or, D. Ben-Amitai, H. Yogev and A. Zvulunov, "A Dead Sea Water-Enriched Body Cream Improves Skin Severity Scores in Children with Atopic Dermatitis," Journal of Cosmetics, Dermatological Sciences and Applications, Vol. 1 No. 3, 2011, pp. 71-78.
  7. Polefka TG, Bianchini RJ, Shapiro S. Interaction of mineral salts with the skin: a literature survey. Int J Cosmet Sci. 2012;34(5):416-423.
  8. Inoue T, Inoue S, Kubota K. Bactericidal activity of manganese and iodide ions against Staphylococcus aureus: a possible treatment for acute atopic dermatitis. Acta Derm Venereol. 1999;79(5):360-362.
  9. Levin, N., Gray, T., Farsi, M., Dorton, D., & Miller, R. (2020). Topical Zinc May Augment Post-Operative Wound Healing, Including Following Mohs Micrographic Surgery: A Review of the Literature. SKIN The Journal of Cutaneous Medicine, 4(5), 395–403.
  10. Subramaniam T, Fauzi MB, Lokanathan Y, Law JX. The Role of Calcium in Wound Healing. International Journal of Molecular Sciences. 2021; 22(12):6486.
  11. Schempp CM, Dittmar HC, Hummler D, et al. Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines. J Invest Dermatol. 2000;115(4):680-686.
  12. Proksch E, Nissen HP, Bremgartner M, Urquhart C. Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin. Int J Dermatol. 2005;44(2):151-157.
  13. Nourbakhsh SM, Rouhi-Boroujeni H, Kheiri M, et al. Effect of Topical Application of the Cream Containing Magnesium 2% on Treatment of Diaper Dermatitis and Diaper Rash in Children A Clinical Trial Study. J Clin Diagn Res. 2016;10(1):WC04-WC6.
  14. Sasaki Y, Sathi GA, Yamamoto O. Wound healing effect of bioactive ion released from Mg-smectite. Mater Sci Eng C Mater Biol Appl. 2017;77:52-57.
  15. Denda M, Katagiri C, Hirao T, Maruyama N, Takahashi M. Some magnesium salts and a mixture of magnesium and calcium salts accelerate skin barrier recovery. Arch Dermatol Res. 1999;291(10):560-563.
  16. Lee, Sung Hoon & Min, Dae & Na, Yongjoo & Shim, Jongwon & Kwon, Lee & Cho, Jun-Cheol & Lee, Hae. (2013). The Protective Effect of Mineral Water Against UVB Irradiation. Journal of the Society of Cosmetic Scientists of Korea. 39. 10.15230/SCSK.2013.39.1.039.
  17. Tamura, Bhertha. (2012). A historical review of mineral water Revisão histórica das águas termais. Surgical and Cosmetic Dermatology. 4. 254.
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